Atkinson PW et al. 1993
- Authors:
Atkinson PW. Warren WD. O'Brochta DA.
- Title:
The hobo transposable element of Drosophila can be cross-mobilized in
houseflies and excises like the Ac element of maize.
- Reference location:
Proceedings of the National Academy of Sciences of the United States of
America. 90(20):9693-7, 1993 Oct 15.
- Abstract:
The hobo transposable element from Drosophila melanogaster was found to be
capable of excision, resulting in donor sites unlike those reported for
any other transposable element currently known in animals. These empty
sites most closely resemble those left by the transposable elements Ac and
Tam3 in Zea mays and Antirrhinum majus, respectively. Like Ac and Tam3,
the hobo element was found to function in a distantly related species, in
this case the housefly Musca domestica. Hobo excision in M. domestica was
found not to require the expression of hobo-encoded transposase but
instead appears to be driven by an endogenous hobo transposase-like
activity. DNA sequences displaying high homology to the hobo transposase
gene were isolated from the genome of M. domestica and appear to be part
of a mobile-element system related to hobo, Ac, and Tam3.
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